Clinical, neurophysiological and histopathological profile of patients with neuropathic pain secondary to leprosy from a referral service in southeastern Brazil

Objectives To describe the clinical, neurophysiological and histopathological profile of patients with leprosy neuropathy neuropathic pain from a referral service for in southeastern Brazil. Results Among data analyzed, we found statistically significant correlation between duration associated pain, also age patient number nerves affected nerve conduction studies. We inverse relationship score SF-36 “general health” domain, suggesting worse quality life among these patients. identified presence inflammatory infiltrate biopsy most reaction, scores “pain” domain patients; together suggest that reaction is risk factor occurrence pain. Treatment multidrug regimen does not prevent or interrupt development neuropathy, reinforced present study which majority had undergone previous treatment another portion received during study. Conclusion conclude knowledge about factors characteristics potential importance to outline strategies early identification this manifestation, addition demonstrating negatively impacts life, further reinforces topic neurologic practice.